INTRODUCTION AND OBJECTIVES: Introduction: monosymptomatic nocturnal enuresis is a common problem among children. Treatment modalities vary according to the assumed etiological theories. Assessment of severity and predicting response to treatment can help in management of such a problem. objective: we evaluated the sociodemographic factors as well as the role of ultrasound measured bladder volume and bladder wall thickness in predicting severity and response to behavioral therapy.

METHODS: Subjects and methods: 122 children, 68 boys and 54 girls, aged 5-9 years, 50 of them lived in rural areas while 72 were from urban areas. Children underwent ultrasound evaluation of bladder volume and bladder wall thickness and then calculation of bladder volume wall index. They were treated using the first line management (behavioral therapy) for 4 months. Correlation of severity and treatment response to both sociodemographic variables and ultrasound bladder measurements were done.

RESULTS: Results: only 74 children continued the study, 16 (21.6%) had complete response to treatment, 25 (33.8%) had good response, 18 (24.3%) showed partial response and 15 children (20.3%) showed no response to treatment. Age, gender and residency had no correlation to severity or to treatment response. Ultrasound measured bladder volume also did not correlate to severity or response. Bladder wall thickness showed solid correlation to both severity and response to treatment. This was the same for bladder volume wall index.

CONCLUSIONS: Conclusion: ultrasound measured bladder parameters are strongly related to severity of nocturnal enuresis and are highly predictive for treatment response.

Source of Funding: Zagazig University